Anxiety and depression and its correlates in patients with coronavirus disease 2019 in Wuhan.

Nie, Xue-Dan; Wang, Qin; Wang, Min-Nan; Zhao, Shuai; Liu, Lei; Zhu, Yu-Lan; Chen, Hong

OBJECTIVES Coronavirus disease 2019 (COVID-19) first broke-out in Wuhan China in December 2019, and spread throughout the entire country within a short time. This cross-sectional study investigated the prevalence of depression and anxiety and associated risk factors were analysed in patients with COVID-19. METHODS This single-center cross-sectional study focussed on measuring depression and anxiety using self-report scales. Linear regression was used to determine independent predictors for depression and anxiety. RESULTS A total of 78 patients who were confirmed to have COVID-19 were enrolled in the study. Prevalence of depression and anxiety symptoms were diagnosed in 35.9% and 38.5% of the patients, respectively. Multivariate linear regression analysis found female gender was an independent predictor for higher depression severity index. Having family members who were diagnosed with COVID-19 and family members who died from COVID-19 were independently associated with higher depression severity index and anxiety score. CONCLUSIONS Patients with COVID-19 especially those who had family members diagnosed with COVID-19 or died from COVID-19 were more susceptible to depression and anxiety than were other patients. Effective strategies should be pursued to improve the mental health of this patient population. Key points Patients with COVID-19 showed a significantly high prevalence of depression and anxiety. Female patients were associated with higher risk of depression. Patients with family members diagnosed as COVID-19 or died from this disease were associated with higher risk of depression and anxiety.