Author: Shitao Rao; Alexandria Lau; Hon-Cheong So
Title: Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of 2019-nCov: A Mendelian Randomization analysis Document date: 2020_3_8
ID: myh73pe6_46
Snippet: Similarly, DM was also common in patients infected with MERS-CoV 36,37 . Kulcsar et al. built a mouse model susceptible to MERS-CoV infection and induced type 2 DM using a high-fat diet. They found that, if affected by the virus, these diabetic mice suffered from a prolonged phase of disease and delayed recovery, which might be due to a dysregulated immune response 38 . With regards to comorbidity with cancers, Liang et al. recently carried out a.....
Document: Similarly, DM was also common in patients infected with MERS-CoV 36,37 . Kulcsar et al. built a mouse model susceptible to MERS-CoV infection and induced type 2 DM using a high-fat diet. They found that, if affected by the virus, these diabetic mice suffered from a prolonged phase of disease and delayed recovery, which might be due to a dysregulated immune response 38 . With regards to comorbidity with cancers, Liang et al. recently carried out a nationwide analysis of 1,590 patients with laboratory-confirmed COVID-19 and suggested that cancer patients might have a higher infection risk than those without 39 . The study also reported higher risk of severe complications in such patients.
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