Selected article for: "ciliary motility and ENKUR function"
Author: Monika Abedin Sigg; Tabea Menchen; Jeffery Johnson; Chanjae Lee; Semil P. Choksi; Galo Garcia; Henriette Busengdal; Gerard Dougherty; Petra Pennekamp; Claudius Werner; Fabian Rentzsch; Nevan Krogan; John B. Wallingford; Heymut Omran; Jeremy F. Reiter
Title: Evolutionary proteomics uncovers ciliary signaling components
  • Document date: 2017_6_22
    • ID: 9y8r277c_47
    Snippet: To assess the effect of the homozygous mutation on ENKUR, we examined the motile 465 cilia of nasal epithelial cells isolated from the respiratory tracts of both affected individuals and 466 an unaffected control. We found that human ENKUR localizes to nasal epithelial cilia ( (Table S8 ). Whereas individuals with disrupted ciliary motility produce 487 reduced levels of nasal nitric oxide (Lundberg et al., 1994) , the nasal nitric oxide productio.....
    Document: To assess the effect of the homozygous mutation on ENKUR, we examined the motile 465 cilia of nasal epithelial cells isolated from the respiratory tracts of both affected individuals and 466 an unaffected control. We found that human ENKUR localizes to nasal epithelial cilia ( (Table S8 ). Whereas individuals with disrupted ciliary motility produce 487 reduced levels of nasal nitric oxide (Lundberg et al., 1994) , the nasal nitric oxide production 488 rates of the two individuals with situs inversus were 155 ml/min and 234 ml/min, exceeding the 489 77 ml/min production rate below which is consistent with PCD (Table S8 ). According to these 490 measures, the respiratory ciliary function of both individuals with homozygous ENKUR 491 mutations was normal. 492

    Search related documents:
    Co phrase search for related documents
    • ciliary function and epithelial cilia: 1, 2, 3
    • ciliary function and respiratory tract: 1, 2, 3
    • ciliary motility and ENKUR homozygous mutation: 1
    • ciliary motility and epithelial cell: 1
    • ciliary motility and epithelial cilia: 1, 2
    • ciliary motility and homozygous mutation: 1
    • ciliary motility and nitric oxide: 1
    • ciliary motility and respiratory tract: 1, 2
    • ENKUR homozygous mutation and epithelial cilia: 1
    • ENKUR homozygous mutation and homozygous mutation: 1
    • epithelial cell and ml min: 1
    • epithelial cell and nasal epithelial cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
    • epithelial cell and nitric oxide: 1, 2, 3, 4, 5, 6, 7
    • epithelial cell and respiratory tract: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
    • epithelial cilia and homozygous mutation: 1
    • epithelial cilia and nasal epithelial cilia: 1
    • epithelial cilia and nitric oxide: 1
    • epithelial cilia and respiratory tract: 1, 2, 3, 4
    • homozygous mutation and ml min: 1