Selected article for: "blood brain barrier and cerebrospinal fluid"

Author: Bellon, Mathilde; Schweblin, Cecilia; Lambeng, Nathalie; Cherpillod, Pascal; Vazquez, Jessica; Lalive, Patrice H; Schibler, Manuel; Deffert, Christine
Title: Cerebrospinal fluid features in SARS-CoV-2 RT-PCR positive patients
  • Cord-id: glv8db7h
  • Document date: 2020_8_8
  • ID: glv8db7h
    Snippet: This study analyzed the cerebrospinal fluid features of 31 COVID-19 patients with neurological complications. We observed neither SARS-CoV-2 RNA in the cerebrospinal fluid, nor intrathecal IgG synthesis, but did observe signs of blood-brain barrier disruption. These results might serve as a basis for a better understanding of SARS-CoV-2 related neuropathogenesis.
    Document: This study analyzed the cerebrospinal fluid features of 31 COVID-19 patients with neurological complications. We observed neither SARS-CoV-2 RNA in the cerebrospinal fluid, nor intrathecal IgG synthesis, but did observe signs of blood-brain barrier disruption. These results might serve as a basis for a better understanding of SARS-CoV-2 related neuropathogenesis.

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