Author: Maoz Gelbart; Adi Stern
Title: Evolutionary rate shifts suggest species-specific adaptation events in HIV-1 and SIV Document date: 2017_9_19
ID: npd2qf7m_14
Snippet: Since group M is the pandemic strain of HIV-1, we initially expected that it would experience the 229 highest number of rate shift events among all HIV-1 groups, indicating more efficient adaptation 230 to its human host. Surprisingly, our analysis revealed that group O had almost twice the amount 231 of rate shift events, despite being a non-pandemic strain that remained localized mainly to 232 infections in west-central Africa [55, 56] . We sug.....
Document: Since group M is the pandemic strain of HIV-1, we initially expected that it would experience the 229 highest number of rate shift events among all HIV-1 groups, indicating more efficient adaptation 230 to its human host. Surprisingly, our analysis revealed that group O had almost twice the amount 231 of rate shift events, despite being a non-pandemic strain that remained localized mainly to 232 infections in west-central Africa [55, 56] . We suggest that the number of rate shift events is not 233 the determinant of a pandemic strain; it may rather reflect the relative height of the species 234 barrier a strain had to overcome, as chimpanzee from which group M originated is genetically 235 closer to human than gorilla from which group O originated [57, 58] . 236
Search related documents:
Co phrase search for related documents- high number and human host: 1, 2, 3, 4, 5
- high number and pandemic strain: 1, 2, 3, 4
- human host and pandemic strain: 1, 2, 3
- human host and rate shift: 1, 2
- non pandemic strain and pandemic strain: 1
Co phrase search for related documents, hyperlinks ordered by date