Author: Rauch, Jennifer N.; Valois, Eric; Solley, Sabrina C.; Braig, Friederike; Lach, Ryan S.; Audouard, Morgane; Ponce-Rojas, Jose Carlos; Costello, Michael S.; Baxter, Naomi J.; Kosik, Kenneth S.; Arias, Carolina; Acosta-Alvear, Diego; Wilson, Maxwell Z.
Title: A Scalable, Easy-to-Deploy, Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material Cord-id: hy1xrw6q Document date: 2020_8_29
ID: hy1xrw6q
Snippet: The COVID-19 pandemic has created massive demand for widespread, distributed tools for detecting SARS-CoV-2 genetic material. The hurdles to scalable testing include reagent and instrument accessibility, availability of highly-trained personnel, and large upfront investment. Here we showcase an orthogonal pipeline we call CREST (Cas13-based, Rugged, Equitable, Scalable Testing) that addresses some of these hurdles. Specifically, CREST pairs commonplace and reliable biochemical methods (PCR) with
Document: The COVID-19 pandemic has created massive demand for widespread, distributed tools for detecting SARS-CoV-2 genetic material. The hurdles to scalable testing include reagent and instrument accessibility, availability of highly-trained personnel, and large upfront investment. Here we showcase an orthogonal pipeline we call CREST (Cas13-based, Rugged, Equitable, Scalable Testing) that addresses some of these hurdles. Specifically, CREST pairs commonplace and reliable biochemical methods (PCR) with low-cost instrumentation, without sacrificing detection sensitivity. By taking advantage of simple fluorescence visualizers, CREST allows for a binary interpretation of results. CREST may provide a point- of-care solution to increase the distribution of COVID-19 surveillance.
Search related documents:
Co phrase search for related documents- accurate widelyavailable and long term compliance: 1
- accurate widelyavailable testing and long term compliance: 1
- acid sequence and low cost solution: 1
Co phrase search for related documents, hyperlinks ordered by date