Author: Miele, Monica; Busà , Rosalia; Russelli, Giovanna; Sorrentino, Maria Concetta; Di Bella, Mariangela; Timoneri, Francesca; Mularoni, Alessandra; Panarello, Giovanna; Vitulo, Patrizio; Conaldi, Pier Giulio; Bulati, Matteo
Title: Impaired antiâ€SARSâ€CoVâ€2 humoral and cellular immune response induced by Pfizerâ€BioNTech BNT162b2 mRNA vaccine in solid organ transplanted patients Cord-id: 9k59g9q7 Document date: 2021_6_18
ID: 9k59g9q7
Snippet: SARS-CoV-2 vaccine is considered the primary health strategy able to end the current COVID-19 pandemic. This viral infection impacts more severely solid organ transplant recipients (SOTRs) than general population, but the effect of vaccination in this subgroup of immunosuppressed patients is not known due to their exclusion from vaccination trials. Preliminary reports suggest a lower antibody production after BNT162b2 Pfizer/BioNTech mRNA-vaccine1,2,3,4 , but no data are currently available on t
Document: SARS-CoV-2 vaccine is considered the primary health strategy able to end the current COVID-19 pandemic. This viral infection impacts more severely solid organ transplant recipients (SOTRs) than general population, but the effect of vaccination in this subgroup of immunosuppressed patients is not known due to their exclusion from vaccination trials. Preliminary reports suggest a lower antibody production after BNT162b2 Pfizer/BioNTech mRNA-vaccine1,2,3,4 , but no data are currently available on the elicited virus-specific T cell responses.
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