Author: Ingrid Arevalo-Rodriguez; Diana Buitrago-Garcia; Daniel Simancas-Racines; Paula Zambrano-Achig; Rosa del Campo; Agustin Ciapponi; Omar Sued; Laura Martinez-Garcia; Anne Rutjes; Nicola Low; Jose A Perez-Molina; Javier Zamora
Title: FALSE-NEGATIVE RESULTS OF INITIAL RT-PCR ASSAYS FOR COVID-19: A SYSTEMATIC REVIEW Document date: 2020_4_21
ID: g8h6trql_15
Snippet: We aimed to include all types of RT-PCR kits, regardless of the brand/manufacturer, the RNA 121 extraction method used, the number of target gene assays assessed and cycle threshold value for 122 positivity. Studies comparing the accuracy of two or more tests for COVID-19 diagnosis were also 123 considered if we could abstract the fraction of negative test results as defined by an initial RT-PCR 124 assay. 125.....
Document: We aimed to include all types of RT-PCR kits, regardless of the brand/manufacturer, the RNA 121 extraction method used, the number of target gene assays assessed and cycle threshold value for 122 positivity. Studies comparing the accuracy of two or more tests for COVID-19 diagnosis were also 123 considered if we could abstract the fraction of negative test results as defined by an initial RT-PCR 124 assay. 125
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