Author: Ingrid Arevalo-Rodriguez; Diana Buitrago-Garcia; Daniel Simancas-Racines; Paula Zambrano-Achig; Rosa del Campo; Agustin Ciapponi; Omar Sued; Laura Martinez-Garcia; Anne Rutjes; Nicola Low; Jose A Perez-Molina; Javier Zamora
Title: FALSE-NEGATIVE RESULTS OF INITIAL RT-PCR ASSAYS FOR COVID-19: A SYSTEMATIC REVIEW Document date: 2020_4_21
ID: g8h6trql_43
Snippet: We use the range of false-negative proportions to develop a summary of findings following the 251 GRADE approach. The quality of the evidence was judged to be very low due to issues related to the 252 risk of bias, indirectness, and inconsistency ( Figure 5) . We illustrate the consequences of the range 253 of false-negative proportions in a population of 100 tested, according to three different prevalence 254 seen in the current clinical practic.....
Document: We use the range of false-negative proportions to develop a summary of findings following the 251 GRADE approach. The quality of the evidence was judged to be very low due to issues related to the 252 risk of bias, indirectness, and inconsistency ( Figure 5) . We illustrate the consequences of the range 253 of false-negative proportions in a population of 100 tested, according to three different prevalence 254 seen in the current clinical practice for participant stakeholders (30%, 50%, and 80%) ( Figure 5 ). 255
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