Author: Feaugas, Thomas; Sauvonnet, Nathalie
Title: Organ-on-chip to investigate host-pathogens interactions. Cord-id: h0b2k5f5 Document date: 2021_4_2
ID: h0b2k5f5
Snippet: Infectious diseases remain the subject of intense research. This topic reaches a new era towards the study of host-pathogen interactions mechanisms at the tissue scale. The past few years have hence witnessed the emergence of new methods. Among them, organ-on-chip, which combines biomaterial technology, microfluidic and tissue engineering to recreate the organ physiology is very promising. This review summarizes how this technology recapitulates the architecture, the mechanical stimulation and t
Document: Infectious diseases remain the subject of intense research. This topic reaches a new era towards the study of host-pathogen interactions mechanisms at the tissue scale. The past few years have hence witnessed the emergence of new methods. Among them, organ-on-chip, which combines biomaterial technology, microfluidic and tissue engineering to recreate the organ physiology is very promising. This review summarizes how this technology recapitulates the architecture, the mechanical stimulation and the interface of a tissue and how this particular microenvironment is critical to study host-pathogen interactions. This article is protected by copyright. All rights reserved.
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