Selected article for: "apoptosis hallmark and cell death"
Author: Donia, Ahmed; Bokhari, Habib
Title: Apoptosis induced by SARS-CoV-2: can we target it?
  • Cord-id: 9nwumgzv
  • Document date: 2021_1_29
    • ID: 9nwumgzv
    Snippet: Some viruses are known to be associated with increased apoptosis. Apoptotic cell death triggered by these viruses has a complex role in host antiviral immunity, and might facilitate the viral clearance or act as a mechanism for virus-induced tissue injury and disease progression. The induction of apoptosis is a hallmark of SARS-CoV-2 infection. Accumulating evidence suggests that there is a direct relationship between apoptosis rate and COVID‐19 pathogenicity/severity. Targeting virus-induced
    Document: Some viruses are known to be associated with increased apoptosis. Apoptotic cell death triggered by these viruses has a complex role in host antiviral immunity, and might facilitate the viral clearance or act as a mechanism for virus-induced tissue injury and disease progression. The induction of apoptosis is a hallmark of SARS-CoV-2 infection. Accumulating evidence suggests that there is a direct relationship between apoptosis rate and COVID‐19 pathogenicity/severity. Targeting virus-induced apoptosis could be a promising strategy in the treatment of SARS-CoV-2 virus infection.

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