Feasibility Study of Mitigation and Suppression Intervention Strategies for Controlling COVID-19 Outbreaks in London and Wuhan

Po Yang; Jun Qi; Shuhao Zhang; Xulong Wang; Gaoshan Bi; Yun Yang; Bin Sheng

deaths in 1920s, to recent ongoing global outbreaks of coronavirus disease 2019 (COVID-19) killing over 11 thousands people in all over the world [2] , infectious disease is a leading contributor to significant mortality and causes huge losses to society as well as personal family burden. Among a variety of factors leading to emergence and outbreaks of ID, the key issues are population density and human mobility where in these cities with developed transportation systems, pathogens can be spread to large geographic space within a short period of time. For instance, the ongoing global epidemic outbreak of COVID-19 has spread to at least 146 countries and territories on 6 continents in 2 months. In order to give an accurate prediction of outbreaks, many researchers have been working in traditional ID propagation models [3] [4] [5] [6] [7] like SIR, SEIR,.et.al, for understanding COVID-19 transmission with human mobility and predicting outbreak process of epidemics. Meanwhile, as realizing a long period of this battle against COVID-19, many of them recently focus on intervention strategies [8] [9] [10] that can balance a trade-off between limited human mobility and potential economic loss in COVID-19 control. It poses an important research area that explores how and when to take what level of interventions in light of multiple natures and capabilities of countries.