Author: Atianand, Maninjay K.; Fitzgerald, Katherine A.
Title: Long non-coding RNAs and control of gene expression in the immune system Cord-id: jcfe36u6 Document date: 2014_11_1
ID: jcfe36u6
Snippet: All cells of the immune system rely on a highly integrated and dynamic gene expression program that is controlled by both transcriptional and post-transcriptional mechanisms. Recently, non-coding RNAs, including long non-coding RNAs (lncRNA), have emerged as important regulators of gene expression in diverse biological contexts. Long non-coding RNAs control gene expression in the nucleus by modulating transcription or via post-transcriptional mechanisms targeting the splicing, stability or trans
Document: All cells of the immune system rely on a highly integrated and dynamic gene expression program that is controlled by both transcriptional and post-transcriptional mechanisms. Recently, non-coding RNAs, including long non-coding RNAs (lncRNA), have emerged as important regulators of gene expression in diverse biological contexts. Long non-coding RNAs control gene expression in the nucleus by modulating transcription or via post-transcriptional mechanisms targeting the splicing, stability or translation of mRNAs. Our knowledge of lncRNA biogenesis, their cell-type specific expressions, and their versatile molecular functions are rapidly progressing in all areas of biology. Here we discuss these exciting new regulators and highlight an emerging paradigm of lncRNA-mediated control of gene expression in the immune system.
Search related documents:
Co phrase search for related documents- adaptive innate and additional study: 1
- adaptive innate and lncrna gene: 1
- adaptive innate and lncrnas aberrant expression: 1
- adaptive innate and lncrnas control: 1
- adaptive innate and lncrnas expression: 1
- adaptive innate and lncrnas function: 1
- adaptive innate and lncrnas importance: 1
- adaptive innate and lncrnas play: 1
- adaptive innate and lncrnas role: 1
- adaptive innate and lymphoid cell: 1, 2, 3, 4, 5, 6, 7
- adaptive innate and lymphoid cell specific: 1
- adaptive innate and lymphoid tissue: 1, 2, 3, 4
Co phrase search for related documents, hyperlinks ordered by date