Author: Vohora, Divya; Jain, Shreshta; Tripathi, Manjari; Potschka, Heidrun
Title: COVIDâ€19 and seizures: Is there a link? Cord-id: iqnx6qkv Document date: 2020_9_17
ID: iqnx6qkv
Snippet: The rapid spread of the SARSâ€CoVâ€2 pandemic poses particular challenges to the management of persons with chronic disease. Reports of a possible neuroinvasiveness of SARSâ€CoVâ€2 as well as pathophysiological mechanisms and indirect consequences in severe COVIDâ€19 cases raise the question of whether the infection can be associated with an increased risk of seizure recurrence or the development of new onset and acute symptomatic seizures. Although the literature does not provide relevant
Document: The rapid spread of the SARSâ€CoVâ€2 pandemic poses particular challenges to the management of persons with chronic disease. Reports of a possible neuroinvasiveness of SARSâ€CoVâ€2 as well as pathophysiological mechanisms and indirect consequences in severe COVIDâ€19 cases raise the question of whether the infection can be associated with an increased risk of seizure recurrence or the development of new onset and acute symptomatic seizures. Although the literature does not provide relevant evidence for seizure worsening in persons with epilepsy during the course of a SARSâ€CoVâ€2 infection, there are theoretical risks, for example, seizures triggered by fever. Moreover, a severe disease course and advanced disease stages can, for instance, result in hypoxic encephalopathy, cerebrovascular events, and cytokine storm, which may trigger the development of acute seizures. This is further confirmed by reports of occasional seizures in COVIDâ€19 patients. Although the low number of reports so far suggests that the risk may be relatively low, the reports indicate that an early neurological manifestation with seizures should not be ruled out. In the context of these cases, we discuss possible pathophysiological mechanisms that may trigger ictogenesis in patients with SARSâ€CoVâ€2 infection.
Search related documents:
Co phrase search for related documents- abnormal finding and lung function: 1
- abnormal finding and lymph node: 1
- ace function and acute onset: 1
- ace function and acute sars cov respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6
- ace function and lung function: 1, 2, 3, 4, 5
- ace function and magnetic resonance: 1
- ace inhibitor and acute onset: 1
- ace inhibitor and acute phase: 1
- ace inhibitor and acute sars cov respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- ace inhibitor and lung alveolar: 1
Co phrase search for related documents, hyperlinks ordered by date