Selected article for: "case report and central nervous system"
Author: Gorgone, Gaetano; Giudice, Francesco Del; David, Piero; Franco, Giovanni; Giofrè, Laura; Grillo, Gaetano; Iellamo, Mattia Anna; Mastrandrea, Carmela; Orlando, Concetta; Vecchio, Antonino; Galati, Franco
Title: SERUM NEGATIVE NEUROMYELITIS OPTICA SPECTRUM DISORDER AFTER VAXZEVRIA VACCINATION: A CASE REPORT
  • Cord-id: pdlgt2u6
  • Document date: 2021_9_8
    • ID: pdlgt2u6
    Snippet: Background Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease, targeting the central nervous system, rarely associated with vaccination. Case report we report a case of a 47 year-old healthy woman who presented, ten days after the first dose of SARS-CoV-2 Vaccine AstraZeneca (Vaxzevria), with back pain, tetraplegia, urinary retention, dysarthria and dysphagia. The patient was diagnosed NMOSD. She underwent intravenous-corticosteroids, vein-Immunoglobulin and plasma-excha
    Document: Background Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease, targeting the central nervous system, rarely associated with vaccination. Case report we report a case of a 47 year-old healthy woman who presented, ten days after the first dose of SARS-CoV-2 Vaccine AstraZeneca (Vaxzevria), with back pain, tetraplegia, urinary retention, dysarthria and dysphagia. The patient was diagnosed NMOSD. She underwent intravenous-corticosteroids, vein-Immunoglobulin and plasma-exchange without significant improvement . Conclusion The absence of any possible related conditions, the temporal relation with anti-SARS-CoV-2 vaccination, suggest that, in our case, NMOSD may be due to the cross reaction from Vaxzevria.

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