Author: Iwanaga, Yuto; Kawanami, Toshinori; Yamasaki, Kei; Sakakibara, Hideki; Ikushima, Issei; Ikegami, Hiroaki; Tahara, Masahiro; Akata, Kentaro; Mukae, Hiroshi; Yatera, Kazuhiro
Title: A fatal case of COVID-19-associated invasive pulmonary aspergillosis Cord-id: m1f9ojo5 Document date: 2021_4_1
ID: m1f9ojo5
Snippet: A 79-year-old Japanese man with polymyalgia rheumatica was admitted to hospital with coronavirus disease (COVID-19). On admission, he was treated with ciclesonide inhalation, ivermectin, and meropenem. He was intubated 6 days after admission, and methylprednisolone therapy was initiated (1000 mg/day). Hypoxemia and chest radiographic findings temporarily improved. However, chest computed tomography showed bilateral ground-glass attenuations, multiple nodules, and consolidation. Aspergillus fumig
Document: A 79-year-old Japanese man with polymyalgia rheumatica was admitted to hospital with coronavirus disease (COVID-19). On admission, he was treated with ciclesonide inhalation, ivermectin, and meropenem. He was intubated 6 days after admission, and methylprednisolone therapy was initiated (1000 mg/day). Hypoxemia and chest radiographic findings temporarily improved. However, chest computed tomography showed bilateral ground-glass attenuations, multiple nodules, and consolidation. Aspergillus fumigatus was cultured from the tracheal aspirate and he was diagnosed with COVID-19-associated invasive pulmonary aspergillosis (CAPA) and treated with liposomal amphotericin B. However, he died 28 days after admission.
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