Author: Woodall, Maximillian N. J.; Masonou, Tereza; Case, Katieâ€Marie; Smith, Claire M.
Title: Human models for COVIDâ€19 research Cord-id: 8g7ixs5e Document date: 2021_8_17
ID: 8g7ixs5e
Snippet: Currently, therapeutics for COVIDâ€19 are limited. To overcome this, it is important that we use physiologically relevant models to reproduce the pathology of infection and evaluate the efficacy of antiviral drugs. Models of airway infection, including the use of a human infection challenge model or wellâ€defined, disease relevant in vitro systems can help determine the key components that perpetuate the severity of the disease. Here, we briefly review the human models that are currently being
Document: Currently, therapeutics for COVIDâ€19 are limited. To overcome this, it is important that we use physiologically relevant models to reproduce the pathology of infection and evaluate the efficacy of antiviral drugs. Models of airway infection, including the use of a human infection challenge model or wellâ€defined, disease relevant in vitro systems can help determine the key components that perpetuate the severity of the disease. Here, we briefly review the human models that are currently being used in COVIDâ€19 research and drug development.
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