Selected article for: "estimate number and reproductive number"
Author: Joseph T. Wu; Corey M. Peak; Gabriel M. Leung; Marc Lipsitch
Title: Fractional Dosing of Yellow Fever Vaccine to Extend Supply: A Modeling Study
  • Document date: 2016_5_14
    • ID: ejqq2wmi_2
    Snippet: Findings 36 We estimate the effective reproductive number early in the Angola outbreak was between 5·2 37 and 7·1. If vaccine action is all-or-nothing (i.e. a proportion VE of vaccinees receives complete 38 and the remainder receive no protection), n-fold fractionation can dramatically reduce IAR as 39 long as efficacy VE exceeds 1/n. This benefit threshold becomes more stringent if vaccine action 40.....
    Document: Findings 36 We estimate the effective reproductive number early in the Angola outbreak was between 5·2 37 and 7·1. If vaccine action is all-or-nothing (i.e. a proportion VE of vaccinees receives complete 38 and the remainder receive no protection), n-fold fractionation can dramatically reduce IAR as 39 long as efficacy VE exceeds 1/n. This benefit threshold becomes more stringent if vaccine action 40

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