Author: Zhang, Linqi; Zhang, Fengwen; Yu, Wenjie; He, Tian; Yu, Jian; Yi, Christopher E.; Ba, Lei; Li, Wenhui; Farzan, Michael; Chen, Zhiwei; Yuen, Kwokâ€Yung; Ho, David
Title: Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals Cord-id: a77g9rjo Document date: 2005_11_18
ID: a77g9rjo
Snippet: Most of the SARSâ€CoVâ€infected patients spontaneously recovered without clinical intervention while a small percentage succumbed to the disease. Here, we characterized temporal changes in N proteinâ€specific and S glycoproteinâ€specific neutralizing antibody (Nab) responses in infected patients who have either recovered from or succumbed to SARSâ€CoV infection. Recovered patients were found to have higher and sustainable levels of both N proteinâ€specific and S glycoproteinâ€specific Nab
Document: Most of the SARSâ€CoVâ€infected patients spontaneously recovered without clinical intervention while a small percentage succumbed to the disease. Here, we characterized temporal changes in N proteinâ€specific and S glycoproteinâ€specific neutralizing antibody (Nab) responses in infected patients who have either recovered from or succumbed to SARSâ€CoV infection. Recovered patients were found to have higher and sustainable levels of both N proteinâ€specific and S glycoproteinâ€specific Nab responses, suggesting that antibody responses likely play an important role in determining the ultimate disease outcome of SARSâ€CoVâ€infected patients. J. Med. Virol. 78:1–8, 2006. © 2005 Wileyâ€Liss, inc.
Search related documents:
Co phrase search for related documents- accession number and acute respiratory syndrome: 1, 2, 3
- accession number and live virus: 1
- acute phase and live virus: 1, 2, 3, 4, 5, 6
- acute respiratory syndrome and live virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- acute respiratory syndrome and local ethic committee: 1
- acute respiratory syndrome and loss dysfunction: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- acute respiratory syndrome and luciferase activity: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- live virus and loss dysfunction: 1
- live virus and luciferase activity: 1
- luciferase activity and madison wi: 1, 2, 3, 4, 5
- luciferase activity and madison wi promega: 1, 2, 3, 4, 5
Co phrase search for related documents, hyperlinks ordered by date