Author: Ting Ding; Jinjin Zhang; Tian Wang; Pengfei Cui; Zhe Chen; Jingjing Jiang; Su Zhou; Jun Dai; Bo Wang; Suzhen Yuan; Wenqing Ma; Lingwei Ma; Yueguang Rong; Jiang Chang; Xiaoping Miao; Xiangyi Ma; Shixuan Wang
Title: A Multi-hospital Study in Wuhan, China:Protective Effects of Non-menopause and Female Hormones on SARS-CoV-2 infection Document date: 2020_3_30
ID: lplodn60_46
Snippet: AMH levels were positively associated with the number of oocytes retrieved, ovarian response, E2 and testosterone 16 . Logistics regression analyses showed that the levels of E2 and AMH in non-severe group are higher than that of the severe group, which may play vital roles in the progression of COVID-19. In this study, non-severe females have higher levels of testosterone than do severe patients. Previous studies have shown that testosterone has.....
Document: AMH levels were positively associated with the number of oocytes retrieved, ovarian response, E2 and testosterone 16 . Logistics regression analyses showed that the levels of E2 and AMH in non-severe group are higher than that of the severe group, which may play vital roles in the progression of COVID-19. In this study, non-severe females have higher levels of testosterone than do severe patients. Previous studies have shown that testosterone has suppressive effects on immune system, such as on cytokine production and lymphocyte proliferation 17 . However, after adjusted by age, the significance became unobvious. In the disease progression of COVID-19, testosterone may work by suppressing immune storms. Our results also indicated that E2 has a stronger protective effect against the potential negative effects from testosterone.
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