Author: Afari, Henrietta; Tefera, Leben; Rosovsky, Rachel P
Title: Case of right ventricular and aortic thrombi in a patient with severe COVID-19 Cord-id: xw8dg31r Document date: 2021_4_19
ID: xw8dg31r
Snippet: Emerging evidence suggests that novel COVID-19 is associated with increased prothrombotic state and risk of thromboembolic complications, particularly in severe disease. COVID-19 is known to predispose to both venous and arterial thrombotic disease. We describe a case of a 61-year-old woman with history of type II diabetes, hypertension and hyperlipidaemia who presented with dry cough and acute abdominal pain. She was found to have a significantly elevated D-dimer, prompting imaging that showed
Document: Emerging evidence suggests that novel COVID-19 is associated with increased prothrombotic state and risk of thromboembolic complications, particularly in severe disease. COVID-19 is known to predispose to both venous and arterial thrombotic disease. We describe a case of a 61-year-old woman with history of type II diabetes, hypertension and hyperlipidaemia who presented with dry cough and acute abdominal pain. She was found to have a significantly elevated D-dimer, prompting imaging that showed thrombi in her right ventricle and aorta. She had rapid clinical deterioration and eventually required tissue plasminogen activator with subsequent durable clinical improvement. This case highlights a rare co-occurrence of venous and arterial thrombi in a patient with severe COVID-19. Further studies are needed to clarify the molecular mechanism of COVID-19 coagulopathy, the utility of D-dimer to predict and stratify risk of thrombosis in COVID-19, and the use of fibrinolytic therapy in patients with COVID-19.
Search related documents:
Co phrase search for related documents- abdomen pelvis and acute respiratory distress syndrome: 1, 2, 3, 4
- abdomen pelvis and lmwh weight heparin: 1
- abdominal aorta and acute respiratory distress syndrome: 1
- abdominal aorta and lmwh weight heparin: 1
- abdominal pain and acute abdominal pain: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- abdominal pain and acute respiratory distress syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
- abdominal pain and lmwh weight heparin: 1
- abdominal pain and lymphocyte count: 1, 2, 3, 4, 5, 6, 7, 8, 9
- abdominal tenderness and acute abdominal pain: 1, 2, 3, 4, 5, 6
Co phrase search for related documents, hyperlinks ordered by date