Author: Ruslan, Aliya; Williams, David M; Purnell, Oliver; Edwards, Rhodri; Peter, Raj; Stephens, Jeffrey W; Chudleigh, Richard
Title: A physician's approach and experience of managing patients with diabetes during COVIDâ€19 Cord-id: 8kteo1sz Document date: 2021_4_8
ID: 8kteo1sz
Snippet: Since the start of the COVIDâ€19 pandemic, the vulnerability of people with diabetes has been recognised with a greater risk of morbidity and mortality compared to the general population. The outcomes associated with diabetes may be a consequence of an impaired immune response, presence of composite comorbidities or the multiâ€organ infectivity of SARSâ€CoVâ€2 affecting the pancreas. Emerging evidence suggests that both acute and chronic hyperglycaemia can exacerbate the clinical consequence
Document: Since the start of the COVIDâ€19 pandemic, the vulnerability of people with diabetes has been recognised with a greater risk of morbidity and mortality compared to the general population. The outcomes associated with diabetes may be a consequence of an impaired immune response, presence of composite comorbidities or the multiâ€organ infectivity of SARSâ€CoVâ€2 affecting the pancreas. Emerging evidence suggests that both acute and chronic hyperglycaemia can exacerbate the clinical consequences of COVIDâ€19. Thus, the role of health care professionals in the observation and management of glucose control is increasingly recognised in people with diabetes in both the acute and chronic setting. In this review, we highlight the key biological implications of SARSâ€CoVâ€2 infection in people with diabetes, the clinical outcomes of COVIDâ€19 in people with diabetes and management principles with respect to glucose control including our local experiences. Copyright © 2021 John Wiley & Sons.
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