Author: Enrico Lavezzo; Michele Berselli; Ilaria Frasson; Rosalba Perrone; Giorgio Palù; Alessandra R. Brazzale; Sara N. Richter; Stefano Toppo
Title: G-quadruplex forming sequences in the genome of all known human viruses: a comprehensive guide Document date: 2018_6_11
ID: c3lmmll6_2
Snippet: Expansion of G4-forming motifs were associated with relevant human neurological disorders (Fry and Loeb 1994; Sket et al. 2015; Zhou et al. 2015) . In RNA, G4s were mapped in mRNAs and in non-coding RNAs (ncRNAs), such as long non-coding RNAs (lncRNAs) (Jayaraj et al. 2012 ) and precursor microRNAs (pre-miRNAs) (Mirihana Arachchilage et al. 2015) indicating the potential of RNA G4s to regulate both pre-and post-transcriptional gene expression (Ag.....
Document: Expansion of G4-forming motifs were associated with relevant human neurological disorders (Fry and Loeb 1994; Sket et al. 2015; Zhou et al. 2015) . In RNA, G4s were mapped in mRNAs and in non-coding RNAs (ncRNAs), such as long non-coding RNAs (lncRNAs) (Jayaraj et al. 2012 ) and precursor microRNAs (pre-miRNAs) (Mirihana Arachchilage et al. 2015) indicating the potential of RNA G4s to regulate both pre-and post-transcriptional gene expression (Agarwala et al. 2015; Cammas and Millevoi 2017) . RNA G4s were also suggested to affect DNA processes (Takahama et al. 2013; Hirashima and Seimiya 2015; Zheng et al. 2015) .
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