A comparative multi-centre study on the clinical and imaging features of comfirmed and uncomfirmed patients with COVID-19

Congliang Miao; Jinqiang Zhuang; Mengdi Jin; Huanwen Xiong; Peng Huang; Qi Zhao; Li Miao; Jiang Du; Xinying Yang; Peijie Huang; Jiang Hong

With the spread of the epidemic, 2019 coronavirus disease , the new disease caused by SARS-Cov-2, broke out nationwide and worldwide, especially China, Italy, South Korea, Iran. As to March 10, 2020, a total of 80924 laboratory-confirmed cases had been reported in China, and 32778 confirmed cases overseas, which represents a trend of global spread(4). On 11 March 2020, the world health organization declared the COVID-19 as a global pandemic. Theoretically, the most effective strategy for epidemic is early diagnosis, quarantine and treatment. Therefore, how to diagnose COVID-19 early is of great importance. It's now the period of seasonal influenza, and the clinical symptoms of COVID-19 are similar to common respiratory diseases (influenza, common cold, viral pneumonia, etc.), which indicates the differential diagnosis are difficult for clinicians. At present, the diagnostic gold standard for studies had described the differences in clinical characteristics between ICU and non-ICU patients (7) (8) (9) (10) , however very few scientists focused on confirmed and unconfirmed groups (11) . Therefore, we described and compared the epidemiological history, clinical, laboratory characteristics and imaging features between confirmed and unconfirmed COVID-19 groups aim to providing a reference for the COVID-19 differential diagnosis, prevention and treatment.