Author: Mélanie Legrand; Sophie Bachellier-Bassi; Keunsook K. Lee; Yogesh Chaudhari; Hélène Tournu; Laurence Arbogast; Hélène Boyer; Murielle Chauvel; Vitor Cabral; Corinne Maufrais; Audrey Nesseir; Irena Maslanka; Emmanuelle Permal; Tristan Rossignol; Louise A. Walker; Ute Zeidler; Sadri Znaidi; Floris Schoeters; Charlotte Majgier; Renaud A. Julien; Laurence Ma; Magali Tichit; Christiane Bouchier; Patrick Van Dijck; Carol A. Munro; Christophe d’Enfert
Title: Generating genomic platforms to study Candida albicans pathogenesis Document date: 2018_2_8
ID: 1vx62ofn_56
Snippet: The analysis of the 6,880,620 nucleotides of the 5,102 sequence-validated ORFs revealed 2077 SNPs. These nucleotide substitutions could be real SNPs between our strain and the reference strain, or due to poor quality of some reference sequences, or mutations in the primers, or misincorporation by the DNA polymerase. Overall, the resulting maximum error rate amounts to 3 x 10 -4 or 1 SNP every 3,312 cloned nucleotides. Notably, the C. albicans SC5.....
Document: The analysis of the 6,880,620 nucleotides of the 5,102 sequence-validated ORFs revealed 2077 SNPs. These nucleotide substitutions could be real SNPs between our strain and the reference strain, or due to poor quality of some reference sequences, or mutations in the primers, or misincorporation by the DNA polymerase. Overall, the resulting maximum error rate amounts to 3 x 10 -4 or 1 SNP every 3,312 cloned nucleotides. Notably, the C. albicans SC5314 genome sequence available at CGD (version_A22-s07-m01-r18) contained 272
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