Author: Joseph T. Wu; Corey M. Peak; Gabriel M. Leung; Marc Lipsitch
Title: Fractional Dosing of Yellow Fever Vaccine to Extend Supply: A Modeling Study Document date: 2016_5_14
ID: ejqq2wmi_34
Snippet: Even more unlikely, in our opinion, is that fractionated doses would be substantially less 287 efficacious according to a "leaky" model, in which all vaccinated individuals were imperfectly 288 protected against infection from each infectious bite, with the same probability of infection 289 from each bite, reduced by vaccine by a proportion VE (see appendix for details). If this were 290 the case however, we found that especially in high-transmis.....
Document: Even more unlikely, in our opinion, is that fractionated doses would be substantially less 287 efficacious according to a "leaky" model, in which all vaccinated individuals were imperfectly 288 protected against infection from each infectious bite, with the same probability of infection 289 from each bite, reduced by vaccine by a proportion VE (see appendix for details). If this were 290 the case however, we found that especially in high-transmission areas, the fractionated-dose 291
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