Author: Gupta, Aashish; Kachur, Sergey M.; Tafur, Jose D.; Patel, Harsh K.; Timme, Divina O.; Shariati, Farnoosh; Rogers, Kristen D.; Morin, Daniel P.; Lavie, Carl J.
Title: Development and validation of a multivariable risk prediction model for COVID-19 mortality in the Southern United States Cord-id: hjih9vc3 Document date: 2021_9_17
ID: hjih9vc3
Snippet: Objective To evaluate clinical characteristics of COVID-19 admitted patients in Southern United States and development as well as validation of a mortality risk prediction model. Patients and methods Southern Louisiana was an early hot-spot in the pandemic, which provided a large collection of clinical data on inpatients with COVID-19. We designed a risk stratification model to assess admitted COVID patients’ mortality risk. Data from 1673 consecutive patients diagnosed with COVID-19 infection
Document: Objective To evaluate clinical characteristics of COVID-19 admitted patients in Southern United States and development as well as validation of a mortality risk prediction model. Patients and methods Southern Louisiana was an early hot-spot in the pandemic, which provided a large collection of clinical data on inpatients with COVID-19. We designed a risk stratification model to assess admitted COVID patients’ mortality risk. Data from 1673 consecutive patients diagnosed with COVID-19 infection and hospitalized between 03/01/2020 to 04/30/2020 was used to create an 11-factor mortality risk model based on baseline comorbidity, organ injury, and laboratory results. The risk model was validated using a subsequent cohort of 2067 consecutive hospitalized patients admitted between 06/01/2020 to 12/31/2020. Results The resultant model has an area under the curve of 0.783 (95% confidence interval 0.76-0.81), with an optimal sensitivity of 0.74 and specificity of 0.69 for predicting mortality. Validation of this model in a subsequent cohort of 2067 consecutively hospitalized patients yielded comparable prognostic performance. Conclusion We have developed an easy-to-use, robust model for systematically evaluating patients presenting to acute care settings with COVID infection.
Search related documents:
Co phrase search for related documents- acute kidney injury and adjusted odd ratio: 1, 2
- acute kidney injury and admission age: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- acute kidney injury and admission assessment score: 1, 2, 3
- acute kidney injury and admission kidney injury: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58
- liver disease and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67
- liver disease and logistic regression model: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- liver disease and low mortality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- liver disease and low mortality rate: 1
- liver disease and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61
- liver disease and lung injury: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23
- logistic regression and low community prevalence: 1
- logistic regression and low mortality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64
- logistic regression and low mortality rate: 1, 2, 3, 4, 5, 6, 7, 8, 9
- logistic regression and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- logistic regression and lung injury: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- logistic regression model and low mortality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- logistic regression model and low mortality rate: 1, 2, 3
- logistic regression model and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- logistic regression model and lung injury: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date