Selected article for: "cardiovascular disease and hypertension chronic respiratory disease"
Author: Quan Li; Zanxia Cao; Proton Rahman
Title: Genetic Variability of Human Angiotensin-Converting Enzyme 2 (hACE2) Among Various Ethnic Populations
  • Document date: 2020_4_15
    • ID: bbn1tfq5_3
    Snippet: Differences among the host, particularly the sex of the patient and presence of selected co-morbid diseases and immunosuppressive state have been identified as risk factors from severe Covid-192,3. Pre-existing medical conditions have been associated with increased prevalence of death including: cardiovascular disease (13.2%); diabetes (9.2%); chronic respiratory disease (8.0%); hypertension (8.4%) and recent diagnosis of cancer (7.6%) 4. Specifi.....
    Document: Differences among the host, particularly the sex of the patient and presence of selected co-morbid diseases and immunosuppressive state have been identified as risk factors from severe Covid-192,3. Pre-existing medical conditions have been associated with increased prevalence of death including: cardiovascular disease (13.2%); diabetes (9.2%); chronic respiratory disease (8.0%); hypertension (8.4%) and recent diagnosis of cancer (7.6%) 4. Specifically, hypertensive patients had a hazard ratio of 1.70 for death 5 and 3.05 for in-hospital mortality 4. An increased association with the use of angiotensinconverting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) has been reported for severe Covid-19 cases6. A biologically plausible link between SARS-CoV-2 infections and ACE inhibition has been proposed 7.

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