Author: Hongyi Chen; Zhicheng Zhang; Li Wang; Zhihua Huang; Fanghua Gong; Xiaodong Li; Yahong Chen; Jinzi J. WU
Title: First Clinical Study Using HCV Protease Inhibitor Danoprevir to Treat Naive and Experienced COVID-19 Patients Document date: 2020_3_24
ID: b3y9zxjr_18
Snippet: The key parameters of 11 patients were presented in Table 2 and illustrated graphically in Figure 1 . In general, nine patients experienced lopinavir/ritonavir along with interferon nebulization treatment were enrolled and switched to danoprevir/ritonavir treatment, including four patients with interferon nebulization and five patients without interferon nebulization after switching. Two naive patients received danoprevir/ritonavir plus interfero.....
Document: The key parameters of 11 patients were presented in Table 2 and illustrated graphically in Figure 1 . In general, nine patients experienced lopinavir/ritonavir along with interferon nebulization treatment were enrolled and switched to danoprevir/ritonavir treatment, including four patients with interferon nebulization and five patients without interferon nebulization after switching. Two naive patients received danoprevir/ritonavir plus interferon nebulization treatment. After initiation of danoprevir/ritonavir treatment, the first negative RT-PCR test occurred at a median of 2 days, ranging from 1 to 8 days, and the obvious absorption in CT scans occurred at a median 3 days, ranging from 2 to 4 days.
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