Selected article for: "single nucleotide and viral genome"
Author: Enrico Lavezzo; Michele Berselli; Ilaria Frasson; Rosalba Perrone; Giorgio Palù; Alessandra R. Brazzale; Sara N. Richter; Stefano Toppo
Title: G-quadruplex forming sequences in the genome of all known human viruses: a comprehensive guide
  • Document date: 2018_6_11
    • ID: c3lmmll6_35
    Snippet: Among them, Herpesviridae is not only the one with the highest G4 content, but most of its members display significantly more G4 patterns than expected in both genome strands and in all considered G-island lengths. Notably, some of the viruses belonging to Herpesviridae Nonetheless, the overall number of viruses whose G4 content is significantly different with respect to simulated data is higher when real viral genomes are compared to those gener.....
    Document: Among them, Herpesviridae is not only the one with the highest G4 content, but most of its members display significantly more G4 patterns than expected in both genome strands and in all considered G-island lengths. Notably, some of the viruses belonging to Herpesviridae Nonetheless, the overall number of viruses whose G4 content is significantly different with respect to simulated data is higher when real viral genomes are compared to those generated by single nucleotide assembling. This difference indicates that viral genome k-mer composition is indeed affecting the probability of randomly finding G4 patterns, at least in a proportion of viruses as shown in Figure 4 : in the heatmaps, viruses that are significant in only one of the two simulations are reported for GG-and GGG-island patterns, whereas no such cases were found for GGGG-type G4s. author/funder. All rights reserved. No reuse allowed without permission.

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