Author: S. Willis; J. Masel
Title: Gene birth contributes to structural disorder encoded by overlapping genes Document date: 2017_12_6
ID: 9w2wjiik_3
Snippet: In this work we explore three non-mutually-exclusive hypotheses why this might be, and quantify the extent of each. Two have previously been considered: that elevated ISD in overlapping genes is a mechanism that relieves evolutionary constraint, and that elevated ISD is a holdover from the de novo gene birth process. We add consideration of a third, previously-unexplored hypothesis -that elevated ISD with dual-coding may be the result of an artif.....
Document: In this work we explore three non-mutually-exclusive hypotheses why this might be, and quantify the extent of each. Two have previously been considered: that elevated ISD in overlapping genes is a mechanism that relieves evolutionary constraint, and that elevated ISD is a holdover from the de novo gene birth process. We add consideration of a third, previously-unexplored hypothesis -that elevated ISD with dual-coding may be the result of an artifact of the genetic code -to the mix.
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