Author: Kevin W. Graepel; Maria L. Agostini; Xiaotao Lu; Nicole R. Sexton; Mark R. Denison
Title: Fitness barriers limit reversion of a proofreading-deficient coronavirus Document date: 2019_4_26
ID: 8pr10j88_2
Snippet: Assuming an ExoN-AA mutation rate of 10 -4 µ and accounting for codon degeneracy, the 115 probability of restoring the native amino acid sequence in a single round of replication is 10 -18 . 116.....
Document: Assuming an ExoN-AA mutation rate of 10 -4 µ and accounting for codon degeneracy, the 115 probability of restoring the native amino acid sequence in a single round of replication is 10 -18 . 116
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