Author: Gerardo Chowell; Ranu Dhillon; Devabhaktuni Srikrishna
Title: Getting to zero quickly in the 2019-nCov epidemic with vaccines or rapid testing Document date: 2020_2_5
ID: 4sw1hrnf_4
Snippet: In order to bring R below 1, we contrasted two alternate strategies by modeling the proportion of the population that needs to be protected from infection by one-time vaccination (assuming 100% effectiveness) or by testing with isolation and treatment of individuals within six, 24, or 48 hours of symptom onset. We employed an SEIR-type transmission model [5] where the mean incubation period is 5 days, mean infectious period is 7 days, and the ini.....
Document: In order to bring R below 1, we contrasted two alternate strategies by modeling the proportion of the population that needs to be protected from infection by one-time vaccination (assuming 100% effectiveness) or by testing with isolation and treatment of individuals within six, 24, or 48 hours of symptom onset. We employed an SEIR-type transmission model [5] where the mean incubation period is 5 days, mean infectious period is 7 days, and the initial prevalence of the novel coronavirus (2019-nCov) infections is at 0.1% in a population of 10 million, roughly the population of Wuhan. In light of the unknowns with asymptomatic transmission, a fixed percentage of the transmission is modeled prior to symptom onset.
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