Author: Mohammad Saeed; Alejandro Ibáñez-Costa; Alejandra María Patiño-Trives; Eduardo Collantes Estevez; María Ángeles Aguirre; Chary López-Pedrera
Title: Genomic convergence of locus-based GWAS meta-analysis identifies DDX11 as a novel Systemic Lupus Erythematosus gene Document date: 2020_4_18
ID: 27szdvgd_4
Snippet: Previously, OASIS analysis of two dbGAP GWAS datasets (6077 subjects; 0.75 million SNPs) identified thirty SLE associated loci (Saeed, 2017b) . In the present study, 410 genes were mapped to these loci and investigated for gene expression in three SLE GEO datasets. A fourth expression dataset from Cordoba, Spain was used for validation......
Document: Previously, OASIS analysis of two dbGAP GWAS datasets (6077 subjects; 0.75 million SNPs) identified thirty SLE associated loci (Saeed, 2017b) . In the present study, 410 genes were mapped to these loci and investigated for gene expression in three SLE GEO datasets. A fourth expression dataset from Cordoba, Spain was used for validation.
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