Author: Vergaraâ€Alert, J.; Raj, V. S.; Muñoz, M.; Abad, F. X.; Cordón, I.; Haagmans, B. L.; Bensaid, A.; Segalés, J.
Title: Middle East respiratory syndrome coronavirus experimental transmission using a pig model Cord-id: m8miwtha Document date: 2017_6_26
ID: m8miwtha
Snippet: Dromedary camels are the main reservoir of Middle East respiratory syndrome coronavirus (MERSâ€CoV), but other livestock species (i.e., alpacas, llamas, and pigs) are also susceptible to infection with MERSâ€CoV. Animalâ€toâ€animal transmission in alpacas was reported, but evidence for transmission in other species has not been proved. This study explored pigâ€toâ€pig MERSâ€CoV transmission experimentally. Virus was present in nasal swabs of infected animals, and limited amounts of viral
Document: Dromedary camels are the main reservoir of Middle East respiratory syndrome coronavirus (MERSâ€CoV), but other livestock species (i.e., alpacas, llamas, and pigs) are also susceptible to infection with MERSâ€CoV. Animalâ€toâ€animal transmission in alpacas was reported, but evidence for transmission in other species has not been proved. This study explored pigâ€toâ€pig MERSâ€CoV transmission experimentally. Virus was present in nasal swabs of infected animals, and limited amounts of viral RNA, but no infectious virus were detected in the direct contact pigs. No virus was detected in the indirect contact group. Furthermore, direct and indirect contact pigs did not develop specific antibodies against MERSâ€CoV. Therefore, the role of pigs as reservoir is probably negligible, although it deserves further confirmation.
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