Author: Große, Karsten; Kramer, Matthijs; Trautwein, Christian; Bruns, Tony
Title: SARSâ€CoVâ€2 as an extrahepatic precipitator of acuteâ€onâ€chronic liver failure Cord-id: mgr32ftl Document date: 2020_5_29
ID: mgr32ftl
Snippet: We read with great interest the report by Qiu and colleages reporting the first case of acute-on-chronic liver failure (ACLF) following SARS-CoV-2 infection. Based on elevated transaminases, jaundice, and coagulopathy, the authors discuss hepatic virus entry and systemic inflammation as possible underlying mechanisms. As ACLF following hepatic versus extrahepatic insults may differ in presentation, course, and prognosis, we herein report the case of a patient with ACLF precipitated by extrahepat
Document: We read with great interest the report by Qiu and colleages reporting the first case of acute-on-chronic liver failure (ACLF) following SARS-CoV-2 infection. Based on elevated transaminases, jaundice, and coagulopathy, the authors discuss hepatic virus entry and systemic inflammation as possible underlying mechanisms. As ACLF following hepatic versus extrahepatic insults may differ in presentation, course, and prognosis, we herein report the case of a patient with ACLF precipitated by extrahepatic complications of SARS-CoV-2.
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