Selected article for: "patient group and prospective study"
Author: Karacin, Cengiz; Eren, Tulay; Zeynelgil, Esra; Imamoglu, Goksen Inanc; Altinbas, Mustafa; Karadag, Ibrahim; Basal, Fatma Bugdayci; Bilgetekin, Irem; Sutcuoglu, Osman; Yazici, Ozan; Ozdemir, Nuriye; Ozet, Ahmet; Yildiz, Yesim; Esen, Selin Akturk; Ucar, Gokhan; Uncu, Dogan; Dinc, Bedia; Aykan, Musa Baris; Erturk, İsmail; Karadurmus, Nuri; Civelek, Burak; Çelik, İsmail; Ergun, Yakup; Dogan, Mutlu; Oksuzoglu, Omur Berna
Title: Immunogenicity and safety of the CoronaVac vaccine in patients with cancer receiving active systemic therapy
  • Cord-id: j260p9vq
  • Document date: 2021_8_3
    • ID: j260p9vq
    Snippet: Aim: To evaluate the immunogenicity and safety of the CoronaVac vaccine in patients with cancer receiving active systemic therapy. Methods: This multicenter, prospective, observational study was conducted with 47 patients receiving active systemic therapy for cancer. CoronaVac was administered as two doses (3 μg/day) on days 0 and 28. Antibody level higher than 1 IU/ml was defined as ‘immunogenicity.’ Results: The immunogenicity rate was 63.8% (30/47) in the entire patient group, 59.5% (25/
    Document: Aim: To evaluate the immunogenicity and safety of the CoronaVac vaccine in patients with cancer receiving active systemic therapy. Methods: This multicenter, prospective, observational study was conducted with 47 patients receiving active systemic therapy for cancer. CoronaVac was administered as two doses (3 μg/day) on days 0 and 28. Antibody level higher than 1 IU/ml was defined as ‘immunogenicity.’ Results: The immunogenicity rate was 63.8% (30/47) in the entire patient group, 59.5% (25/42) in those receiving at least one cytotoxic drug and 100% (five of five) in those receiving monoclonal antibody or immunotherapy alone. Age was an independent predictive factor for immunogenicity (odds ratio: 0.830; p = 0.043). Conclusion: More than half of cancer patients receiving active systemic therapy developed immunogenicity.

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