Guideline-based Chinese herbal medicine treatment plus standard care for severe coronavirus disease 2019 (G-CHAMPS): evidence from China

Yong-an Ye

The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03.27.20044974 doi: medRxiv preprint 5 Pharmacopoeia(5). All herbs were tested for heavy metals, microbial contamination, and residual pesticides to ensure they meet the safety standards in China prior to use. Trained and experienced technicians prepared the decoction from the formulas according to a standardized procedure; each unit of formula yielded 400mL of decoction, divided into two equal portions. Nurses administered the decoction 200mL to patients orally (via feeding tube if needed) twice daily for a total of seven days in the CHM plus group. Data were retrieved from electronic medical records using the standardized case record forms which created by members of ISARIC(6) (International Severe Acute Respiratory and Emerging Infection Consortium) in collaboration with the World Health Organization.