Author: Quan Li; Zanxia Cao; Proton Rahman
Title: Genetic Variability of Human Angiotensin-Converting Enzyme 2 (hACE2) Among Various Ethnic Populations Document date: 2020_4_15
ID: bbn1tfq5_5
Snippet: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.14.041434 doi: bioRxiv preprint receptor serves as the host cell entry for SARS-CoV and more recently it has been shown to be receptor for cellular entry for SARS-CoV-2 9,10. As recently reported by Hoffman et al 11, the cellular entry of SARS-CoV-2 can be.....
Document: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.14.041434 doi: bioRxiv preprint receptor serves as the host cell entry for SARS-CoV and more recently it has been shown to be receptor for cellular entry for SARS-CoV-2 9,10. As recently reported by Hoffman et al 11, the cellular entry of SARS-CoV-2 can be blocked by an inhibitor of the cellular serine protease TMPRSS2, which is employed by SARS-CoV-2 for S protein priming. Further attention has been drawn to the ACE2 receptor as antimalarials, which can interfere with ACE2 expression, have resulted in increased clearing of the SARS-CoV-2 clearance among Covid-19 patients 12.
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