Author: Yong-an Ye
Title: Guideline-based Chinese herbal medicine treatment plus standard care for severe coronavirus disease 2019 (G-CHAMPS): evidence from China Document date: 2020_4_1
ID: 4as055wh_22
Snippet: Since this is a pilot randomized trial, sample size calculation was not performed. For pharmaceutical interventions, a minimum sample size of 12 per group was usually recommended as a rule of thumb for a pilot study (7) . Considering a dropout rate of 10%, we aimed to recruit a total sample size of 42 patients (standard care group, n=14; CHM plus group, n=28)......
Document: Since this is a pilot randomized trial, sample size calculation was not performed. For pharmaceutical interventions, a minimum sample size of 12 per group was usually recommended as a rule of thumb for a pilot study (7) . Considering a dropout rate of 10%, we aimed to recruit a total sample size of 42 patients (standard care group, n=14; CHM plus group, n=28).
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