Author: Mohammad Saeed; Alejandro Ibáñez-Costa; Alejandra María Patiño-Trives; Eduardo Collantes Estevez; María Ángeles Aguirre; Chary López-Pedrera
Title: Genomic convergence of locus-based GWAS meta-analysis identifies DDX11 as a novel Systemic Lupus Erythematosus gene Document date: 2020_4_18
ID: 27szdvgd_25
Snippet: Hence, replication based genomic convergence approach with OASIS, and expression studies can help identify novel SLE genes. Measuring DDX11 expression by qPCR in monocytes from SLE patients as described here, can potentially be used as a clinically useful predictive marker for SLE. This may allow early recognition and treatment of SLE possible and may significantly impact prevention of SLE complications......
Document: Hence, replication based genomic convergence approach with OASIS, and expression studies can help identify novel SLE genes. Measuring DDX11 expression by qPCR in monocytes from SLE patients as described here, can potentially be used as a clinically useful predictive marker for SLE. This may allow early recognition and treatment of SLE possible and may significantly impact prevention of SLE complications.
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