Selected article for: "immune response and viral material"
Author: Furth, Noa; Shilo, Shay; Cohen, Niv; Erez, Nir; Fedyuk, Vadim; Schrager, Alexander M.; Weinberger, Adina; Dror, Amiel A.; Zigron, Asaf; Shehadeh, Mona; Sela, Eyal; Srouji, Samer; Amit, Sharon; Levy, Itzchak; Segal, Eran; Dahan, Rony; Jones, Dan; Douek, Daniel C.; Shema, Efrat
Title: Multiplexed Detection of COVID-19 with Single-Molecule Technology
  • Cord-id: kzjhnza3
  • Document date: 2021_5_27
    • ID: kzjhnza3
    Snippet: The COVID-19 pandemic raises the need for diverse diagnostic approaches to rapidly detect different stages of viral infection. The flexible and quantitative nature of single-molecule imaging technology renders it optimal for development of new diagnostic tools. Here we present a proof-of-concept for a single-molecule based, enzyme-free assay for multiplexed detection of SARS-CoV-2. The unified platform we developed allows direct detection of the viral genetic material from patients’ samples, a
    Document: The COVID-19 pandemic raises the need for diverse diagnostic approaches to rapidly detect different stages of viral infection. The flexible and quantitative nature of single-molecule imaging technology renders it optimal for development of new diagnostic tools. Here we present a proof-of-concept for a single-molecule based, enzyme-free assay for multiplexed detection of SARS-CoV-2. The unified platform we developed allows direct detection of the viral genetic material from patients’ samples, as well as their immune response consisting of IgG and IgM antibodies. Thus, it establishes a platform for diagnostics of COVID-19, which could also be adjusted to diagnose additional pathogens.

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