Author: Neha Jain; Subodh Kumar Mishra; Uma Shankar; Arpita Tawani; Ankit Jaiswal; Tarun Kumar Sharma; Prashant Kodgire; Amit Kumar
Title: G-quadruplex stabilization in the ions and maltose transporters inhibit Salmonella enterica growth and virulence Document date: 2018_6_27
ID: 57xx291v_28
Snippet: Next, Electrophoretic Mobility Shift assay (EMSA) was performed to check the molecularity (inter or intra molecular G-quadruplex) of SE-PGQ in the solution. An intramolecular G-quadruplexes possess a compact topology and migrate faster than their linear counterpart, whereas intermolecular G-quadruplex contains a comparatively wider topology and exhibited slow migration than their linear counterpart [52] . All the three SE-PGQs and positive contro.....
Document: Next, Electrophoretic Mobility Shift assay (EMSA) was performed to check the molecularity (inter or intra molecular G-quadruplex) of SE-PGQ in the solution. An intramolecular G-quadruplexes possess a compact topology and migrate faster than their linear counterpart, whereas intermolecular G-quadruplex contains a comparatively wider topology and exhibited slow migration than their linear counterpart [52] . All the three SE-PGQs and positive control (Tel22 DNA G-quadruplex) showed faster mobility than their respective linear counterpart and therefore suggested the formation of intramolecular G-quadruplex by SE-PGQs (Fig 6) .
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