Selected article for: "disease outbreak and transmission route"
Author: Mitsuyama, Keiichi; Tsuruta, Kozo; Takedatsu, Hidetoshi; Yoshioka, Shinichiro; Morita, Masaru; Niwa, Mikio; Matsumoto, Satoshi
Title: Clinical Features and Pathogenic Mechanisms of Gastrointestinal Injury in COVID-19
  • Cord-id: rcc5q3rj
  • Document date: 2020_11_11
    • ID: rcc5q3rj
    Snippet: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the global coronavirus disease 2019 (COVID-19) outbreak. Along with the respiratory tract, the gastrointestinal (GI) tract is one of the main extra-pulmonary targets of SARS-CoV-2 with respect to symptom occurrence and is a potential route for virus transmission, most likely due to the presence of angiotensin-converting enzyme 2. Therefore, understanding the mechanisms of GI injury is crucial for a harmonized therapeuti
    Document: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the global coronavirus disease 2019 (COVID-19) outbreak. Along with the respiratory tract, the gastrointestinal (GI) tract is one of the main extra-pulmonary targets of SARS-CoV-2 with respect to symptom occurrence and is a potential route for virus transmission, most likely due to the presence of angiotensin-converting enzyme 2. Therefore, understanding the mechanisms of GI injury is crucial for a harmonized therapeutic strategy against COVID-19. This review summarizes the current evidence for the clinical features of and possible pathogenic mechanisms leading to GI injury in COVID-19.

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