Selected article for: "disease burden and risk factor"

Author: Cheung, Chi Yuen; Chan, Koon Ming; Tang, Gloria; Cheung, Agnes; Chak, Wai Leung
Title: Immunosuppressive medication adherence in kidney transplant recipients during COVID-19 pandemic: a cross sectional study in Hong Kong
  • Cord-id: l1d66twp
  • Document date: 2021_8_16
  • ID: l1d66twp
    Snippet: BACKGROUND: Coronavirus disease 2019 (COVID-19) pandemic has put an enormous burden on healthcare systems worldwide. Limited access to medical care and fear of increased infective risks due to the use of immunosuppressive medication (IM) have increased concerns about IM adherence in kidney transplant recipients (KTR). The aim of this study is to determine the various dimensions of IM non-adherence in KTR during the COVID-19 pandemic. METHODS: This was a single-center, cross-sectional study using
    Document: BACKGROUND: Coronavirus disease 2019 (COVID-19) pandemic has put an enormous burden on healthcare systems worldwide. Limited access to medical care and fear of increased infective risks due to the use of immunosuppressive medication (IM) have increased concerns about IM adherence in kidney transplant recipients (KTR). The aim of this study is to determine the various dimensions of IM non-adherence in KTR during the COVID-19 pandemic. METHODS: This was a single-center, cross-sectional study using a convenient sampling approach. KTR with follow-up in Queen Elizabeth Hospital, Hong Kong between 1st May 2020 and 30th September 2020 were invited to complete a self-reported questionnaire on IM adherence. The sociodemographic factors associated with IM adherence were extracted from medical record. RESULTS: Total 210 patients completed the questionnaires. The overall IM non-adherence rate was 35.2% in the preceding 4 weeks. None of the patients stopped taking IM without doctors’ instructions. The most common pattern of IM non-adherence was timing adherence (n=63, 30.1%), followed by dose-skipping item. Among the different sociodemographic factors studied, only marital status was an independent risk factor of IM non-adherence (OR: 1.97, 95% CI: 1.04-3.72, P=0.03). CONCLUSION: The impact of COVID-19 on IM adherence in KTR was small. All the patients continued their IM despite of the pandemic. Good family support can have a positive influence on treatment adherence in KTR during the COVID-19 pandemic.

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