Selected article for: "lopinavir ritonavir and lung inflammation"
Author: Kusaba, Yusaku; Izumi, Shinyu; Takasaki, Jin; Suzuki, Manabu; Katagiri, Daisuke; Katsuno, Takashi; Matsumoto, Shuichiro; Sakamoto, Keita; Hashimoto, Masao; Ohmagari, Norio; Katano, Harutaka; Suzuki, Tadaki; Hojo, Masayuki; Sugiyama, Haruhito
Title: Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion
  • Cord-id: pm40ny87
  • Document date: 2020_8_29
    • ID: pm40ny87
    Snippet: An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use
    Document: An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung.

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