Selected article for: "challenge virus and recombinant virus"

Author: Higgins, P G; Phillpotts, R J; Scott, G M; Wallace, J; Bernhardt, L L; Tyrrell, D A
Title: Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers.
  • Cord-id: i8t2n75r
  • Document date: 1983_1_1
  • ID: i8t2n75r
    Snippet: In a double-blind, placebo-controlled study, self-administered intranasal human interferon alpha A produced by recombinant DNA technology was given both before and after virus challenge with a respiratory coronavirus. The incidence of colds, the severity of symptoms and signs, and virus replication were all reduced in subjects receiving interferon as compared with those given placebo.
    Document: In a double-blind, placebo-controlled study, self-administered intranasal human interferon alpha A produced by recombinant DNA technology was given both before and after virus challenge with a respiratory coronavirus. The incidence of colds, the severity of symptoms and signs, and virus replication were all reduced in subjects receiving interferon as compared with those given placebo.

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