Author: Vineet D. Menachery; Lisa E. Gralinski; Hugh D. Mitchell; Kenneth H. Dinnon; Sarah R. Leist; Boyd L. Yount; Eileen T. McAnarney; Rachel L. Graham; Katrina M. Waters; Ralph S. Baric
Title: Combination attenuation offers strategy for live-attenuated coronavirus vaccines Document date: 2018_4_28
ID: 3t75dbb7_5
Snippet: The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) at the 34 beginning of the 21st century signaled a new era for emergent viral disease (1). Since then, 35 dozens of viruses have emerged from animal populations to produce significant outbreaks in 36 humans and transfer of zoonotic pathogens remains a major threat to global public health (2). A 37 decade after SARS-CoV, infections with Middle East respiratory syndrome coron.....
Document: The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) at the 34 beginning of the 21st century signaled a new era for emergent viral disease (1). Since then, 35 dozens of viruses have emerged from animal populations to produce significant outbreaks in 36 humans and transfer of zoonotic pathogens remains a major threat to global public health (2). A 37 decade after SARS-CoV, infections with Middle East respiratory syndrome coronavirus (MERS-38 CoV) continue with periodic reintroductions still occurring six years after its initial discovery (3).
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