Author: Nicola Clementi; Elena Criscuolo; Roberta Antonia Diotti; Roberto Ferrarese; Matteo Castelli; Roberto Burioni; Massimo Clementi; Nicasio Mancini
Title: Combined prophylactic and therapeutic use maximizes hydroxychloroquine anti-SARS-CoV-2 effects in vitro Document date: 2020_3_31
ID: fhy2z49t_2
Snippet: It is therefore important to use this data in order to set up possible scenarios related to the real clinical use of this drug. In this study, we tested HCQ against a SARS-CoV-2 Italian clinical isolate, by using different protocols of drug administration corresponding to its possible prophylactic, therapeutic and prophylactic/therapeutic use in patients. A single HCQ concentration easily reachable in the lung and characterized by high anti-SARS-.....
Document: It is therefore important to use this data in order to set up possible scenarios related to the real clinical use of this drug. In this study, we tested HCQ against a SARS-CoV-2 Italian clinical isolate, by using different protocols of drug administration corresponding to its possible prophylactic, therapeutic and prophylactic/therapeutic use in patients. A single HCQ concentration easily reachable in the lung and characterized by high anti-SARS-CoV-2 activity was used.
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