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Author: Fitz, Wolfgang; Rosenthal, Peter B.; Wong, Chi-Huey
Title: Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus
  • Cord-id: tigrxvzy
  • Document date: 1996_8_31
  • ID: tigrxvzy
    Snippet: Abstract 2-α-Thiomethylmercuryl 9-acetamido-9-deoxy-sialoside was prepared and found to inhibit the 9-O-acetylsialic acid esterase from influenza C virus in a competitive manner with a K i of 4.2±0.5 mM. The inhibitor is being used in the X-ray determination of the crystal structure of the esterase.
    Document: Abstract 2-α-Thiomethylmercuryl 9-acetamido-9-deoxy-sialoside was prepared and found to inhibit the 9-O-acetylsialic acid esterase from influenza C virus in a competitive manner with a K i of 4.2±0.5 mM. The inhibitor is being used in the X-ray determination of the crystal structure of the esterase.

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